By Carlos -

Aging and longevity tied to specific brain region in mice

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ScienceDaily (2010-07-29) — The protein SIRT1 in the brain is tied into a mechanism that allows animals to survive when food is scarce, according to a new study. The research suggests that SIRT1 may be involved with the life span-increasing effect of low-calorie diets, they report.

Sirtuins and aging. It surprises me that this evidence is only just now getting light, but congrats to the researchers who have created these mice lines and did the work to prove an intuitive association of hypothalamic regulatory mechanisms and Sirtuins under a low-calorie state. It’s nice when intuition pans out. This helps to further prop up the anti-aging and lifespan extending effect of Caloric restriction and that of Sirtuin activators such as Resveratrol, which has been shown to extend the lifespan of many lab animal species.

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